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科研喵使用ai读文献,祝你效率百倍,访问labcat.com.cn下载。今天我们关注发表在《Neuro-oncology》(IF: 16.4)上的重要研究"Associations of supramaximal resection with outcome in glioblastoma across age groups: a report of the RANO resect group"。这项国际研究分析了1260例胶质母细胞瘤患者,发现手术切除效果存在年龄差异。虽然完全切除对比增强肿瘤对所有患者都有益,但超最大切除仅在65岁以下初发患者中显著延长生存期(40 vs 20个月)。在复发病例中,最大切除对年轻患者更有利。研究结果支持根据年龄采取分层手术策略,为胶质母细胞瘤的个体化治疗提供了重要依据。