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科研喵使用AI读文献,祝你效率百倍,访问labcat.com.cn下载。今天我们要分享发表在影响因子高达8.6的《European journal of nuclear medicine and molecular imaging》上的重要研究:"Hybrid Tau-PET/MRI study: Quantitative susceptibility mapping in progressive supranuclear palsy and its correlation with Tau-PET"。这项突破性研究发现,通过结合tau-PET和定量磁化率映射(QSM)技术,能够更早地诊断进行性核上性麻痹(PSP),这种疾病常被误诊。研究首次揭示了PSP患者特定脑区域铁积累的独特模式,并证实了铁与tau蛋白病理变化之间存在显著关联。这一发现为开发新型诊断生物标志物开辟了新途径,有望改变PSP的临床诊断和治疗前景。