
In this episode, we delve into how a multi-scale Quantitative Systems Pharmacology model is transforming our understanding of metastatic melanoma. You’ll hear a detailed discussion on integrating lesion-, patient-, and population-level dynamics to uncover hidden progression drivers, dissect mechanism-specific effects of checkpoint inhibitors, and guide the design of next-generation combination therapies. A must-listen for anyone interested in the quantitative modelling revolution in immuno-oncology.
Here is the link to the paper : https://ascpt.onlinelibrary.wiley.com/doi/epdf/10.1002/psp4.12637