In this episode of Updates in Anesthesiology, we discuss one of the most significant airway guideline updates in a decade. The Difficult Airway Society’s 2025 guidelines reshape how we approach unanticipated difficult tracheal intubation in adults. From first-attempt success and videolaryngoscopy for all, to peroxygenation, physiologically difficult airways, linear algorithms, and a renewed emphasis on human factors.
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