The fate of Jerusalem has been inextricably intertwined with that of Rome ever since they joined in unholy alliance to reject and crucify the Lord of glory (Acts 2:23; 1 Corinthians 2:8). That uneasy partnership was shattered with Jerusalem's destruction by Rome's legions in AD 70, foretold both by Daniel (9:26) and Jesus (Matthew 24:2). The Roman Empire must be revived, for one day its armies will belong to Daniel's "prince that shall come"—i.e., Antichrist––and will seek to destroy Jerusalem again.

The woman in Revelation 17 can only be Rome/Vatican City. No other city built on seven hills wields such authority, exchanging ambassadors with nations. Nor does any other city claim to represent Christ, and thus no other could stand accused of spiritual fornication due to unholy alliances with earth's rulers. Neither can any other city rival the blood of both Jews and Christians which pagan Rome and later the Vatican have shed. Thomas Hobbes perceptively said, "The Papacy is...the ghost of the deceased Roman Empire, sitting crowned upon the grave thereof."