In this episode of Better Thinking, Nesh Nikolic speaks with Dr Joanna Moncrieff about her latest book: Chemically Imbalanced: The Making and Unmaking of The Serotonin Myth.

Dr Joanna Moncrieff is a practising psychiatrist, part-time academic, and author with a deep interest in the history, philosophy, and politics of psychiatry. Her work focuses particularly on the use, misuse, and misrepresentation of psychiatric drugs.

She became interested in drug treatment because of its dominance in contemporary approaches to managing the suffering and disturbances labeled as mental disorders. She recognised that embedded in the understanding of drugs such as ‘antipsychotics’ and ‘antidepressants’ was an unexamined assumption: that these drugs ‘work’ by correcting a hypothetical abnormality or ‘chemical imbalance.’ Moncrieff has termed this the ‘disease-centred’ model of drug action and has developed an alternative ‘drug-centred’ model, which highlights the ways psychiatric drugs alter brain and body function, modify feelings and behaviour, and interact with the difficulties associated with mental disorders.

Alongside colleagues from around the world, Moncrieff has worked to expose the misconceptions that arise from the disease-centred model, clarify the effects psychiatric drugs produce, and question the narratives that sustain current prescribing practices.

She also emphasises that psychiatry is a profoundly political enterprise, shaped by social and political imperatives to neutralise distress and manage disturbing behaviour. Beyond her work on psychiatric drugs, she is interested in how emotional and behavioural problems might be conceptualised differently, as well as the broader politics of healthcare.