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Biomanufacturing & Fermentation Technology
prasad ernala
15 episodes
17 hours ago
Welcome to Biomanufacturing & Fermentation Technology, the podcast where microbes meet manufacturing and science turns into scalable reality. In each episode, we dive inside real bioprocesses. from lab-scale experiments to commercial fermenters. to unpack how products are actually made, fixed, and optimized in the real world. Expect candid conversations on fermentation failures and breakthroughs, scale-up war stories, regulatory realities, emerging technologies, and the decisions that separate a promising culture from a profitable process. Whether you are a scientist, engineer, entrepreneur, o
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Science
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All content for Biomanufacturing & Fermentation Technology is the property of prasad ernala and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Welcome to Biomanufacturing & Fermentation Technology, the podcast where microbes meet manufacturing and science turns into scalable reality. In each episode, we dive inside real bioprocesses. from lab-scale experiments to commercial fermenters. to unpack how products are actually made, fixed, and optimized in the real world. Expect candid conversations on fermentation failures and breakthroughs, scale-up war stories, regulatory realities, emerging technologies, and the decisions that separate a promising culture from a profitable process. Whether you are a scientist, engineer, entrepreneur, o
Show more...
Science
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Biology Does Not Scale. Physics Scales.
Biomanufacturing & Fermentation Technology
12 minutes 50 seconds
3 weeks ago
Biology Does Not Scale. Physics Scales.

A Pichia process for a recombinant protein was transferred from 10 L (Lab) to 12,000 L

(GMP). Outcome: Catastrophic failure. Titer dropped 60%, and product quality degraded due to

proteolysis.

Biomanufacturing & Fermentation Technology
Welcome to Biomanufacturing & Fermentation Technology, the podcast where microbes meet manufacturing and science turns into scalable reality. In each episode, we dive inside real bioprocesses. from lab-scale experiments to commercial fermenters. to unpack how products are actually made, fixed, and optimized in the real world. Expect candid conversations on fermentation failures and breakthroughs, scale-up war stories, regulatory realities, emerging technologies, and the decisions that separate a promising culture from a profitable process. Whether you are a scientist, engineer, entrepreneur, o