Investing in Innovation: A Conversation with Sam Libby, President and Managing Director at TCB Capital Advisors

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Blueprint: Inventing the Future. Catalyzing STEAM Access. Closing the Gap.

Mr. D.J. Ferguson, BS, MS, BCMAS, MRSB MRSC

322 episodes

5 days ago

Innovation isn't accidental; it's designed. Welcome to The Blueprint, a show committed to inventing the future and closing the gap between aspiration and achievement. We deconstruct the mechanics of success in modern science to provide access to the insights that matter most. Featuring masterclasses in leadership from icons such as Dr. Robert Langer, Chancellor Gary May, Provost Raheem Beyah, Dr. Todd Golub, and Greg Zuckerman, this is your guide to navigating—and leading—the next era of discovery.

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Investing in Innovation: A Conversation with Sam Libby, President and Managing Director at TCB Capital Advisors

Blueprint: Inventing the Future. Catalyzing STEAM Access. Closing the Gap.

29 minutes 50 seconds

3 months ago

Investing in Innovation: A Conversation with Sam Libby, President and Managing Director at TCB Capital Advisors

🎙️ Episode Description

In this episode, we sit down with Sam Libby,President and Managing Director at TCB Capital Advisors, whose career has been dedicated to transforming healthcare through strategic investments andpartnerships. With more than 30 completed transactions —spanning mergers and acquisitions, capital raises, and innovative deal structures—Sam has become a trusted advisor at the intersection of finance, science, and patient care. Our conversation dives deep into his origin story—from Rutgers to leading one of the most dynamic advisory firms in healthcare—and explores how his investment philosophy balances patient-centered missions withthe financial discipline demanded by markets. Sam shares case studies from groundbreaking ventures like Clairity, the first FDA-cleared AI breast cancer risk platform, and Altoida, a pioneer in early cognitive assessment technology, offering valuable lessons for founders and investors alike.

We also discuss the critical role of strategicpartnerships, the evolving dynamics between founders and investors, and the exciting frontiers shaping the future of healthcare—from oncology and neurodegeneration to women’s health and digital innovation. Sam highlights how AI and data are reshaping deal-making, due diligence, and commercialization pathways.

Finally, Sam offers practical advice for aspiringthought leaders and entrepreneurs on refining their pitch, stepping into leadership beyond the lab, and positioning themselves for long-term impact in a rapidly evolving industry. Whether you’re a scientist, entrepreneur, investor, or future healthcare leader, this episode provides insightful perspectives on the business of innovation, the art of deal-making, and the mission to improvepatient outcomes.