Direct effect PKPD models (Ep. 32)

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Clinical Pharmacology Podcast with Nathan Teuscher

Nathan Teuscher

50 episodes

2 weeks ago

I discuss clinical pharmacology and pharmacometrics topics from the perspective of drug development scientists. I share my expertise and knowledge about designing and conducting clinical pharmacology studies and discuss how to analyze the data using the most effective approaches. I draw from my experience of over 20 years working in drug development organizations and consultancies.

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Direct effect PKPD models (Ep. 32)

Clinical Pharmacology Podcast with Nathan Teuscher

31 minutes 34 seconds

1 year ago

Direct effect PKPD models (Ep. 32)

In this episode I describe direct effect PK-PD models. I describe how they work, a method of creating exploratory plots to identify direct effect models, how to set up the dataset for NONMEM, and how to code the model in NONMEM. This is the first of 4 episodes on different PK-PD models.

Links discussed in the show:

Example NONMEM code for direct effect model
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