Welcome back to season 4 of Curiosity Killed the Rat! This episode, Kade and Matt are chatting all about Testosterone: a hormone that makes you sweaty and hungry and hairy and horny. We often learn about testosterone and its effects on the body in the context of a cisgender male puberty. But testosterone can be important for other individuals, too! This episode, our resident scientist Kade – who has been on testosterone as part of a gender-affirming hormone replacement therapy for several months – will discuss the biology behind testosterone and its effects on the body, specifically through a trans-masculine lens. Kade dives into the different changes that testosterone can cause in the body, like hair growth (and loss!), voice deepening, and muscle changes. Why are some of these changes reversible, while others are permanent? We also tackle a listener question about barking dogs – why don’t males sound deeper? As always, you can find us @curiosityrat on twitter, instagram, and facebook, and send your listener questions in to curiosityrat@gmail.com We also now have a Patreon! If you love our content and want to support us you can jump on to https://www.patreon.com/curiosityrat and become a patron. There is absolutely ZERO pressure but if you have as little as $1/month you can chuck it our way to help us out and show you appreciate all the time and effort that goes into making this show. Episode references: https://www.transhub.org.au/hormones-masculinising https://www.mayoclinic.org/tests-procedures/masculinizing-hormone-therapy/about/pac-20385099 https://transcare.ucsf.edu/article/information-testosterone-hormone-therapy https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12278 https://www.sciencedirect.com/science/article/abs/pii/S000334720400123X https://royalsocietypublishing.org/doi/full/10.1098/rsbl.2013.0926 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432488/ https://pubmed.ncbi.nlm.nih.gov/8770664/#:~:text=Based%20on%20presented%20data%20we,synthase%20within%20the%20corpora%20cavernosa