Medium Article: https://medium.com/@jsmith0475/when-machines-learn-to-negotiate-reimagining-manufacturing-coordination-through-multi-agent-ai-fb6a60fc17eb WebApp: https://main.d2oyp76axtxaek.amplifyapp.com This article, by Dr. Jerry A. Smith, outlines a theoretical framework for revolutionizing complex manufacturing coordination, specifically within the regulated medical device sector, by using Multi-Agent AI (Artificial Intelligence). The core problem addressed is the exponential coordination complexity of running multiple facilities that current centralized enterprise software cannot handle effectively. Dr. Smith proposes a system where specialized AI agents—each an expert in an area like inventory or compliance—would negotiate and coordinate decisions within seconds, significantly improving speed and accuracy over current human-centered, email-based processes. Crucially, this framework advocates for a hybrid intelligence approach combining transparent mathematical formulas with Large Language Models (LLMs) to ensure both adaptability and the explainability required for regulatory audits. While the concept is compelling, the author acknowledges significant practical hurdles including expensive data integration, the need for robust safety mechanisms, and organizational resistance to such a dramatic shift.