From Easter Island soil to modern skin science — meet rapamycin, the molecule that might just change vitiligo care. Once known mainly as an anti-rejection drug for organ transplants, rapamycin is now being tested as a topical treatment that could both calm the immune attack and help pigment return. Early studies look promising: minimal side effects, slow but steady repigmentation, and surprisingly good tolerance. In this episode, we explore: How rapamycin rewires the skin’s immune balance Why it’s called both a suppressor and a rejuvenator What Phase II trials are revealing so far And whether this “longevity drug” might also restore color to the skin It’s too early to call it a breakthrough — but this little molecule from a far-off island might just be the next quiet revolution in vitiligo therapy. Full story: Topical Rapamycin: Could This Be Vitiligo’s Next Big Breakthrough?