A lecture exploring alternatives to using labeled training data. Labeled training data is often scarce, unavailable, or can be very costly to obtain. To circumvent this problem, there is a growing interest in developing methods that can exploit sources of information other than labeled data, such as weak-supervision and zero-shot learning. While these techniques obtained impressive accuracy in practice, both for vision and language domains, they come with no theoretical characterization of their accuracy. In a sequence of recent works, we develop a rigorous mathematical framework for constructing and analyzing algorithms that combine multiple sources of related data to solve a new learning task. Our learning algorithms provably converge to models that have minimum empirical risk with respect to an adversarial choice over feasible labelings for a set of unlabeled data, where the feasibility of a labeling is computed through constraints defined by estimated statistics of the sources. Notably, these methods do not require the related sources to have the same labeling space as the multiclass classification task. We demonstrate the effectiveness of our approach with experimentations on various image classification tasks. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
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A lecture exploring alternatives to using labeled training data. Labeled training data is often scarce, unavailable, or can be very costly to obtain. To circumvent this problem, there is a growing interest in developing methods that can exploit sources of information other than labeled data, such as weak-supervision and zero-shot learning. While these techniques obtained impressive accuracy in practice, both for vision and language domains, they come with no theoretical characterization of their accuracy. In a sequence of recent works, we develop a rigorous mathematical framework for constructing and analyzing algorithms that combine multiple sources of related data to solve a new learning task. Our learning algorithms provably converge to models that have minimum empirical risk with respect to an adversarial choice over feasible labelings for a set of unlabeled data, where the feasibility of a labeling is computed through constraints defined by estimated statistics of the sources. Notably, these methods do not require the related sources to have the same labeling space as the multiclass classification task. We demonstrate the effectiveness of our approach with experimentations on various image classification tasks. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
Causality and Autoencoders in the Light of Drug Repurposing for COVID-19
Department of Statistics
58 minutes
4 years ago
Causality and Autoencoders in the Light of Drug Repurposing for COVID-19
Caroline Uhler (MIT), gives a OxCSML Seminar on Friday 2nd July 2021. Abstract: Massive data collection holds the promise of a better understanding of complex phenomena and ultimately, of better decisions. An exciting opportunity in this regard stems from the growing availability of perturbation / intervention data (genomics, advertisement, education, etc.). In order to obtain mechanistic insights from such data, a major challenge is the integration of different data modalities (video, audio, interventional, observational, etc.). Using genomics as an example, I will first discuss our recent work on coupling autoencoders to integrate and translate between data of very different modalities such as sequencing and imaging. I will then present a framework for integrating observational and interventional data for causal structure discovery and characterize the causal relationships that are identifiable from such data. We then provide a theoretical analysis of autoencoders linking overparameterization to memorization. In particular, I will characterize the implicit bias of overparameterized autoencoders and show that such networks trained using standard optimization methods implement associative memory. We end by demonstrating how these ideas can be applied for drug repurposing in the current COVID-19 crisis.
Department of Statistics
A lecture exploring alternatives to using labeled training data. Labeled training data is often scarce, unavailable, or can be very costly to obtain. To circumvent this problem, there is a growing interest in developing methods that can exploit sources of information other than labeled data, such as weak-supervision and zero-shot learning. While these techniques obtained impressive accuracy in practice, both for vision and language domains, they come with no theoretical characterization of their accuracy. In a sequence of recent works, we develop a rigorous mathematical framework for constructing and analyzing algorithms that combine multiple sources of related data to solve a new learning task. Our learning algorithms provably converge to models that have minimum empirical risk with respect to an adversarial choice over feasible labelings for a set of unlabeled data, where the feasibility of a labeling is computed through constraints defined by estimated statistics of the sources. Notably, these methods do not require the related sources to have the same labeling space as the multiclass classification task. We demonstrate the effectiveness of our approach with experimentations on various image classification tasks. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
