Dr. Datis Kharrazian explains why mitochondrial resilience—not supplements—is the foundation of recovery, energy, and long-term health.

Dr. Datis Kharrazian reframes mitochondria as the core drivers of resilience, recovery, and longevity—not just energy production. He explains why fatigue reflects mitochondrial efficiency, how movement and cognitive challenge stimulate mitochondrial biogenesis, and why sleep and circadian rhythm are essential for cellular repair. This conversation challenges supplement-only approaches and highlights lifestyle-driven strategies that restore endurance, adaptability, and healing capacity.

Dr. Datis Kharrazian is a Harvard-trained researcher, clinician, and educator known for redefining how practitioners approach chronic illness, brain health, and fatigue. With decades of experience training healthcare professionals worldwide, he emphasizes physiology-based healing over protocol-driven care. His work bridges neuroscience, immunology, and lifestyle medicine—helping patients and practitioners restore resilience by addressing mitochondrial function, sleep, movement, and environmental stressors at the root level.