Take a deeper dive into our peer-reviewed emergency medicine content with the EMplify podcast. Join hosts Sam Ashoo, MD and T.R. Eckler, MD for educational, conversational reviews of current evidence guaranteed to help you make your best clinical decisions. Each high-yield episode gives you practical, time-tested guidance from practicing emergency medicine clinicians and subject-matter experts. Listen and learn!
All content for EMplify by EB Medicine is the property of EB Medicine and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Take a deeper dive into our peer-reviewed emergency medicine content with the EMplify podcast. Join hosts Sam Ashoo, MD and T.R. Eckler, MD for educational, conversational reviews of current evidence guaranteed to help you make your best clinical decisions. Each high-yield episode gives you practical, time-tested guidance from practicing emergency medicine clinicians and subject-matter experts. Listen and learn!
In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the October 2025 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Patients With Adrenal InsufficiencyIntroduction* Welcome and host introductions* Brief overview of the episode’s topic* Resources and CME reminderArticle Overview* Source: Emergency Medicine Practice, October 2025* Authors: The Simcoes* Importance of evidence-based reviewClinical Context & Epidemiology* Frequency and rarity of adrenal insufficiency* Diagnostic challenges and statistics* Importance of recognizing adrenal crisisPathophysiology* Primary, secondary, and tertiary adrenal insufficiency* Causes and mechanisms* Key anatomical and physiological conceptsDifferential Diagnosis* Overlap with other diseases (infections, autoimmune, endocrine, psychiatric, cardiac, GI, etc.)* Importance of considering adrenal crisis in complex casesPrehospital Care* EMS recognition and limitations* Importance of medication history and emergency kits* Legal and logistical barriers to prehospital hydrocortisoneEmergency Department Evaluation* Recognizing symptoms and prioritizing care* Role of EMR and clinical decision support* Key history and risk factors (medications, steroid use, opioid use, comorbidities)Physical Examination* Specific and nonspecific findings* Cushingoid features vs. primary adrenal insufficiency signsDiagnostic Workup* Laboratory studies (cortisol, ACTH, renin, aldosterone, TSH, etc.)* Imaging considerations* Gold standard tests and their limitations in the EDTreatment* Immediate administration of hydrocortisone* Dosing for adults and pediatrics* Supportive care (fluids, glucose, treating underlying cause)* Sick day dosing and home managementSpecial Populations* Pregnancy considerations* Septic shock and adrenal crisisCommon Pitfalls & Takeaways* Delaying steroids for labs/diagnosis* Importance of high suspicion and early treatment* Key trivia and learning pointsClosingSummary and final thoughts* Reminders for further reading and CME* Farewell and next episode teaserEmergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
EMplify by EB Medicine
Take a deeper dive into our peer-reviewed emergency medicine content with the EMplify podcast. Join hosts Sam Ashoo, MD and T.R. Eckler, MD for educational, conversational reviews of current evidence guaranteed to help you make your best clinical decisions. Each high-yield episode gives you practical, time-tested guidance from practicing emergency medicine clinicians and subject-matter experts. Listen and learn!
