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FOMO Investing
Brian and Mik
17 episodes
1 month ago
Brian and Mik explore the world of investing through real-world examples and behavioral economics principles.
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Investing
Business
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All content for FOMO Investing is the property of Brian and Mik and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Brian and Mik explore the world of investing through real-world examples and behavioral economics principles.
Show more...
Investing
Business
https://is1-ssl.mzstatic.com/image/thumb/Podcasts221/v4/36/26/d5/3626d5e0-e7a9-9bb1-4dca-2ff9cf25fc50/mza_15456019670194704914.jpg/600x600bb.jpg
Thesis Grading a multi-year investment in TG Therapeutics (TGTX)
FOMO Investing
44 minutes
4 months ago
Thesis Grading a multi-year investment in TG Therapeutics (TGTX)

In this episode of FOMO Investing, Brian O’Neill and Mikhail Bulchandani do a deep dive into one of Brian’s favorite stocks, TG Therapeutics (TGTX).  Brian outlines his multi-year investment thesis in TGTX, from its setbacks in oncology to its successful commercialization of Briumvi (ublituximab) for relapsing forms of multiple sclerosis.


What You’ll Learn:

  • TG Therapeutics’ evolution to a successful commercial-stage biotech. 
  • Practical investment strategies for investing in biotech companies like TGTX.
  • Insights into the multiple sclerosis treatment landscape, and the growing market for anti-CD20 therapies, including Roche's Ocrevus, Novartis’s Kesimpta, and TG’s Briumvi.
  • How Briumvi has been able to gain market traction.
  • Upcoming catalysts for TG Therapeutics, including the potential for a label update to skip the initial dose, the potential to speed up infusions from 1 hour to 30-minutes, and the development of a subcutaneous formulation of Briumvi.
  • A discussion about Bruton’s Tyrosine Kinase inhibitors (BTKi), a new class of disease modifying therapies in clinical trials for the treatment of MS.
  • How TG Therapeutics has positioned itself as a compelling acquisition target.
  • Brian revisits his February 8, 2024 article on TGTX, written when TG was at $14.32.  Recently shares have traded between $35 and $40.  
  • Brian updates his forecast for when TG will achieve a $1 billion net product sales run-rate, and notes that the company today is considerably de-risked with market traction and net positive cash flows.

Links

  • Brian’s February 8, 2024 article on TGTX
  • The Evolution of Anti‑CD20 Treatment for Multiple Sclerosis: Optimization of Antibody Characteristics and Function
  • Progress toward Mitigating Disability Progression in Multiple Sclerosis
FOMO Investing
Brian and Mik explore the world of investing through real-world examples and behavioral economics principles.