From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD.
We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing.
Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story.
If you’re curious, skeptical, and you like learning in public — you’re in the right place.
All content for From First Principles is the property of Krishna Choudhary and Lester Nare and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD.
We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing.
Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story.
If you’re curious, skeptical, and you like learning in public — you’re in the right place.
FFP EP. 11 | From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked
From First Principles
1 hour 54 minutes 25 seconds
3 months ago
FFP EP. 11 | From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked
Hosted by Lester Nare and Krishna Choudhary, this one-episode special brings all three 2025 Nobel Prizes in the sciences into a single listen: Medicine (immune tolerance and FOXP3), Physics (macroscopic quantum tunneling in superconducting circuits), and Chemistry (metal–organic frameworks and “new rooms for chemistry”).
Summary
Medicine: Regulatory T cells and the FOXP3 gene that prevent autoimmune disease.
Physics: Macroscopic quantum tunneling and energy quantization in electrical circuits — the bridge to today’s qubits.
Chemistry: Metal–Organic Frameworks (MOFs) — modular porous crystals enabling CO₂ capture, water harvesting, and hydrogen storage.
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD.
We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing.
Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story.
If you’re curious, skeptical, and you like learning in public — you’re in the right place.
