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From First Principles
Krishna Choudhary and Lester Nare
20 episodes
2 days ago
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.
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All content for From First Principles is the property of Krishna Choudhary and Lester Nare and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.
Show more...
Science
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FFP EP. 3 | Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life
From First Principles
1 hour 16 minutes 46 seconds
5 months ago
FFP EP. 3 | Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life

We go from the universe’s first chemistry to tomorrow’s designer biology, swing by Mars to tune Europa Clipper’s ice radar, and finish with a fresh take on the double-slit experiment.


In this episode

  • The “oldest molecule” puzzle (HeH⁺), cooling the early universe, and why JWST’s findings matter

  • Programmable proteins: reassigning codons, recoding organisms, and real biosafety

  • Europa Clipper’s REASON radar test at Mars: frequencies, ice thickness & ocean clues

  • Double-slit, demystified: single photons, “which-path” info, and measurement reality

Chapters
00:00 Intro

• 01:26 First molecule

• 22:27 Programmable proteins

• 43:05 Europa radar

• 55:00 Double-slit

• 1:15:03 Sign-off

From First Principles
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.