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Trends, tools and transformation: the evolution of flow cytometry in bioanalysis by Taylor & Francis Group
The need for HRMS for quantitation of ADCs vs. QQQ: an interview with Megan Cooley
Future Science Group
21 minutes 35 seconds
12 months ago
The need for HRMS for quantitation of ADCs vs. QQQ: an interview with Megan Cooley
In this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her expert insights into whether HRMS is essential for ADC PK studies. We also tackle the challenges and limitations of HRMS in ADC quantitation and discuss the potential for AI to create more specific and stable ADCs. Finally, Megan highlights ICON’s extensive experience with large molecule applications and their innovative approach to supporting complex LC–MS analyses.
Future Science Group
Trends, tools and transformation: the evolution of flow cytometry in bioanalysis by Taylor & Francis Group
