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Gator PICU Podcast
Christina
17 episodes
3 weeks ago
Send us a text What if a child’s own tumor could teach their immune system how to fight back? We sit down with Dr. Liggon from the University of Florida to unpack a first‑in‑kids, personalized mRNA lipid nanoparticle therapy designed for high‑grade glioma and osteosarcoma. Instead of chasing a single target, this approach isolates mRNA directly from each patient’s tumor and packages it into lipid nanoparticles, training the immune system against a wide range of cancer proteins. That personali...
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Medicine
Health & Fitness
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Send us a text What if a child’s own tumor could teach their immune system how to fight back? We sit down with Dr. Liggon from the University of Florida to unpack a first‑in‑kids, personalized mRNA lipid nanoparticle therapy designed for high‑grade glioma and osteosarcoma. Instead of chasing a single target, this approach isolates mRNA directly from each patient’s tumor and packages it into lipid nanoparticles, training the immune system against a wide range of cancer proteins. That personali...
Show more...
Medicine
Health & Fitness
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Status Asthmaticus
Gator PICU Podcast
49 minutes
1 year ago
Status Asthmaticus
Send us a text Patho/ Background: Asthma flare-ups have two stages: early and late. They start when IgE antibodies produced by certain cells react to triggers such as pollen, dust, animals and many more. These antibodies attach to cells, causing the release of substances like histamines. This release tightens the airways making it harder to breathe. Certain immune cells play a crucial role in producing interleukins that communicate and sustain inflammation. These interleukins support the surv...
Gator PICU Podcast
Send us a text What if a child’s own tumor could teach their immune system how to fight back? We sit down with Dr. Liggon from the University of Florida to unpack a first‑in‑kids, personalized mRNA lipid nanoparticle therapy designed for high‑grade glioma and osteosarcoma. Instead of chasing a single target, this approach isolates mRNA directly from each patient’s tumor and packages it into lipid nanoparticles, training the immune system against a wide range of cancer proteins. That personali...