
How neurotransmitter balance, genetics, and dopamine–glutamate regulation shape ADHD symptoms—and why medication alone often misses the root.
In this episode, we explore the often-missing neurotransmitter layer of ADHD. We discuss how dopamine, glutamate, and genetic differences shape focus, mood, movement, and sleep—and why many ADHD behaviors are the body’s attempt to regulate itself. We also explain why quick labels and medications can overlook infections, airway issues, nutrient imbalances, and environmental triggers. This conversation reframes ADHD as a signal, not a failure, and highlights why root-cause evaluation matters.
Dr. Paula Kruppstadt, MD, IFMCP, is a board-certified pediatrician and Certified Practitioner of Functional Medicine through The Institute for Functional Medicine. As the founder of Hope for Healing, she has dedicated her career to helping children and adults uncover the root causes of complex health challenges. One of the few pediatricians worldwide to hold IFMCP certification, Dr. Kruppstadt is also an expert in PANS/PANDAS and was appointed by Texas Governor Greg Abbott to the state’s Pediatric Acute-onset Neuropsychiatric Syndrome Advisory Council, where she advises on research, diagnosis, treatment, and education for these conditions.
Hope For Healing
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