S1 E5, PUFAs and infection, Part 4: Relevance to human health

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Gut Questions?

12 episodes

5 days ago

Conversational interviews about the gut microbiome between good friends who also work together running DePaolo Lab and CMiST, Center for Microbiome Sciences & Therapeutics, at the University of Washington in Seattle, WA. One friend, Will, is a scientist and knows a sh*t ton about the gut microbiome. The other friend, Parker, is communications specialist for CMiST (aka a Jill-of-all-trades and right-hand man to Will). Join Parker, as she interviews her friend (since 1995) and boss (since 2015), Dr. Will DePaolo, about gut microbiome research, gut health, and nutrition.

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S1 E5, PUFAs and infection, Part 4: Relevance to human health

Gut Questions?

14 minutes 21 seconds

4 years ago

S1 E5, PUFAs and infection, Part 4: Relevance to human health

Episode 5, part 4 – Will talks about why the results from this study are relevant to our everyday lives.

DePaolo Lab ultimately found that the presence of omega-6 polysaturated fatty acids (arachidonic acid was used in this project) worsens inflammation when challenged with virus or bacteria. So, a diet high in omega-6 fatty acids can weaken the immune response to a viral or bacterial infection. Will and I also get into a little discussion about immunity as well as what the lab found when looking at omega-3 fatty acids using the same assays that were used to study omega-6 fatty acids.

DePaolo Lab ultimately found that the presence of omega-6 polysaturated fatty acids (arachidonic acid was used in this project) worsens inflammation when challenged with virus or bacteria. So, a diet high in omega-6 fatty acids can weaken the immune response to a viral or bacterial infection. Will and I also get into a little discussion about immunity as well as what the lab found when looking at omega-3 fatty acids using the same assays that were used to study omega-6 fatty acids.

To check out a figure showing the metabolic pathways of omega-6 and omega-3 visit our Gut Questions? podcast website and go to “Show Notes" → www.yourgutquestions.com/shownotes

If you've gut a question(s) you would like Will to answer in an upcoming episode, email me, Parker, at aparker@medicine.washington.edu or submit a questions on the podcast website, www.yourgutquestions.com/contact

A bunch of our websites and social media platforms:

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Gut Questions? website www.yourgutquestions.com
Gut Questions? Instagram www.instagram.com/gutquestions/

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DePaolo Lab website: www.depaololab.com
DePaolo Lab Instagram: www.instagram.com/depaololab/
DePaolo Lab Twitter: www.twitter.com/depaololab

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CMiST, Center for Microbiome Sciences & Therapeutics: www.cmistuw.org

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Will's LinkedIn: www.linkedin.com/in/williamdepaolo/

#microbiome
#gutmicrobiome
#guthealth
#PUFAS
#polyunsaturated
#fattyacids
#sciencepodcast