A quiet shift in one enzyme may be steering how we age—and how strong we stay. Dr. Helen Blau, trailblazing Stanford scientist and 2025 National Medal of Science honoree, joins us to unpack a breakthrough decades in the making: prostaglandin E2 is essential for muscle stem cell repair, yet a degrading enzyme creeps up with age, draining that signal and eroding strength. Her team calls it a “gerozyme,” and blocking it with a targeted small molecule restored muscle size, power, and endurance in...
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A quiet shift in one enzyme may be steering how we age—and how strong we stay. Dr. Helen Blau, trailblazing Stanford scientist and 2025 National Medal of Science honoree, joins us to unpack a breakthrough decades in the making: prostaglandin E2 is essential for muscle stem cell repair, yet a degrading enzyme creeps up with age, draining that signal and eroding strength. Her team calls it a “gerozyme,” and blocking it with a targeted small molecule restored muscle size, power, and endurance in...
When Running Isn’t Therapy: Katharina Hartmuth on Healing from Trauma & Finding Joy in the Mountains
How We Can Heal
1 hour 30 minutes
1 month ago
When Running Isn’t Therapy: Katharina Hartmuth on Healing from Trauma & Finding Joy in the Mountains
What does it really take to endure when the air thins, the quads burn, and doubt gets loud? We sit down with ultrarunner Katharina Hartmuth—Hardrock and UTMB podium finisher and winner of the 330 km Tor des Géants—to unpack the mental game of mountain ultras and the deeper work that fuels lasting resilience. From long stretches above 12,000 feet to the rare quiet of a small, devoted race community, Katharina explains why Hardrock feels both brutal and beautiful—and why she keeps coming back. ...
How We Can Heal
A quiet shift in one enzyme may be steering how we age—and how strong we stay. Dr. Helen Blau, trailblazing Stanford scientist and 2025 National Medal of Science honoree, joins us to unpack a breakthrough decades in the making: prostaglandin E2 is essential for muscle stem cell repair, yet a degrading enzyme creeps up with age, draining that signal and eroding strength. Her team calls it a “gerozyme,” and blocking it with a targeted small molecule restored muscle size, power, and endurance in...
