S2E9: Breakthroughs: Cell and Gene Based Therapies

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IBDidit

IBDidItPodcast

34 episodes

2 weeks ago

Hi everyone! Our names are Simona and Nadia, and we are two high school students dealing with Inflammatory Bowel Disease. We are here to support and empower other individuals through they're journey, or even just to educate on such an important topic! Each episode will explore different topics to help navigate this crazy journey as we share our own. If you are newly diagnosed or have had it for a long time, our goal is to be honest, authentic, and share our optimism! We also want to thank you for listening to our podcast! We love all our supporters. Follow our instagram @IBDiditpodcast and email us at ibdiditpodcasts@gmail.com! We would love to hear from you! (Episodes are typically 10-20 minutes long!)

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S2E9: Breakthroughs: Cell and Gene Based Therapies

IBDidit

8 minutes

5 months ago

S2E9: Breakthroughs: Cell and Gene Based Therapies

In this episode, we break down what cell and gene-based therapies are and how they’re shaping the future of IBD treatment. From engineered regulatory T-cells to CRISPR-edited genes, these emerging approaches aim to restore immune balance without the broad side effects of traditional treatments. This is such a breakthrough for IBD patients! Be ready to learn and feel the hope :)

Also, follow us on instagram at @ibdiditpodcast and comment more ideas; we would love to hear from you!

Here are all the sources- go check it out! “AstraZeneca Enters Agreement with Quell Therapeutics to Develop Autologous Treg Cell Therapies for Autoimmune Diseases.” AstraZeneca, 13 June 2023,⁠ https://www.astrazeneca.com/media-centre/press-releases/2023/astrazeneca-agreement-with-quell-therapeutics.html⁠.Barnes, Emma L., et al. “Emerging Therapies and Gene Editing in the Management of Autoimmune Disease.” Cell Reports Medicine, vol. 4, no. 9, 2023,⁠ https://www.sciencedirect.com/science/article/pii/S2372770523000621⁠.“CRISPR-Cas9 Gene Editing: Revolutionizing Autoimmune Disease Treatment.” Autoimmune Institute,⁠ https://www.autoimmuneinstitute.org/articles/crispr-cas9-gene-editing-revolutionizing-autoimmune-disease-treatment/⁠.“Major Cause of Inflammatory Bowel Disease Discovered.” Francis Crick Institute, 5 June 2024,⁠ https://www.crick.ac.uk/news-and-reports/2024-06-05_major-cause-of-inflammatory-bowel-disease-discovered⁠.“New Research Discovery Could Change Future of IBD Treatment.” HealthCentral,⁠ https://www.healthcentral.com/news/crohns-disease/new-research-discovery-could-change-future-of-ibd-treatment⁠.“OP22 A Phase 1/2 Study of AZD0466 Monotherapy or in Combination with Anti-TNF in Patients with Moderate-to-Severe Ulcerative Colitis.” Journal of Crohn's and Colitis, vol. 19, Supplement_1, 2025, p. i447,⁠ https://academic.oup.com/ecco-jcc/article/19/Supplement_1/i447/7967034⁠.“Quell Therapeutics Achieves Key Milestone in Its CAR-Treg Cell Therapy Program for Inflammatory Bowel Disease.” GlobeNewswire, 10 June 2025,⁠ https://www.globenewswire.com/news-release/2025/06/10/3096491/0/en/Quell-Therapeutics-Achieves-Key-Milestone-in-its-CAR-Treg-Cell-Therapy-Program-for-Inflammatory-Bowel-Disease.html⁠.