A confusing HIV serology - Trip Gulick, MD/ Frank Maldarelli, MD

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IDBR Infectious Disease Board Review

John Bennett, MD / Henry Masur, MD

22 episodes

6 days ago

The Infectious Disease Board Review (IDBR) Course is designed to help physicians prepare for the American Board of Internal Medicine (ABIM) Infectious Disease certification/recertification exam. This comprehensive review features exam-focused lectures presented by the Nation’s leading infectious disease experts, case-based reviews, online practice exams featuring over 500 ABIM-style and photo-based questions, and additional study guides and primers. https://www.idbrcourse.org/

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A confusing HIV serology - Trip Gulick, MD/ Frank Maldarelli, MD

IDBR Infectious Disease Board Review

4 minutes 16 seconds

1 year ago

A confusing HIV serology - Trip Gulick, MD/ Frank Maldarelli, MD

A 37-year-old woman from New Jersey undergoes routine HIV testing with the following results:

• HIV 4th generation test: Reactive (antibody positive + p24 antigen negative)

• HIV-1/2 Supplemental Assay: HIV-1 antibody negative, HIV-2 antibody negative

• HIV-1 RNA: <20 copies/ml

What is the most likely interpretation of the results?

A. She is a long-term non-progressor

B. She has acute HIV-1 infection

C. She has acute HIV-2 infection

D. She has a false negative viral test

E. She has a false positive 4th generation test