Dr. James MacNamara and Dr. Betty Raman recap the latest annual Hypertrophic Cardiomyopathy Society (HCMS) meeting held in New Orleans. The discussion emphasizes that HCM care is a "team sport," involving a multidisciplinary coalition of physicians, pharmacists, and advanced practice providers. Key highlights include a deep dive into Professor Hugh Watkins' lecture on the future of gene therapy and the impact of polygenic risk scores on disease penetrance. They also explore the evolving landscape of HCM treatment—comparing the roles of cardiac myosin inhibitors versus surgical interventions—and share promising new data on the safety and efficacy of moderate-intensity exercise for non-obstructive patients.