Mitochondrial Replacement Therapy: The Future of Fertility?

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In/Fertility In The City

Infertility In The City

59 episodes

1 week ago

In/Fertility in the City is a podcast dedicated to exploring the complex relationship between in/fertility and work and how to manage this effectively.

It is hosted by Natalie Sutherland and Somaya Ouazzani (and Emma Menzies for Seasons 1-3), who have had to navigate their own fertility challenges alongside professional life, and are united in their passion for ensuring that better quality information and support is made available to others doing the same.

Together they interview incredible guests, from a variety of industries, who generously share powerful stories and valuable insights into in/fertility at work issues.

Their moving and thought-provoking discussions are intended to break the silence around this taboo topic, and inspire new attitudes and behaviours that will improve and normalise the management of fertility challenges in professional contexts.

If you’re a professional managing in/fertility, baby loss, fertility treatment or other paths to parenthood, or you have an interest in understanding and supporting those who are, then this is a ‘must listen’ for you.

TRIGGER WARNING: This podcast deals with discussions of in/fertility and/or baby loss.

You can also engage with your hosts and the growing In/Fertility in the City community by:

emailing us: info@infertilityinthecity.com
following us on LinkedIn ( www.linkedin.com/company/infertilityinthecity ), Instagram ( https://instagram.com/infertilityinthecity ), or X ( https://twitter.com/InFertilityCity ).

Music created by Jon Nicoll.

All content for In/Fertility In The City is the property of Infertility In The City and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

emailing us: info@infertilityinthecity.com
following us on LinkedIn ( www.linkedin.com/company/infertilityinthecity ), Instagram ( https://instagram.com/infertilityinthecity ), or X ( https://twitter.com/InFertilityCity ).

Music created by Jon Nicoll.

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Mitochondrial Replacement Therapy: The Future of Fertility? - with Dr. Uliana Dorofeyeva

In/Fertility In The City

47 minutes

3 weeks ago

Mitochondrial Replacement Therapy: The Future of Fertility? - with Dr. Uliana Dorofeyeva

In this fascinating episode of In/Fertility in the City, host Natalie Sutherland sits down with Dr Uliana Dorofeyeva, a globally recognised fertility specialist and pioneer in mitochondrial replacement therapy (MRT).

Dr Dorofeyeva is the Founder and Medical Director of Ovogene Bank and Advisory Clinical Director at International Fertility Group, with over 18 years’ experience specialising in complex infertility, low ovarian reserve, egg donation, and advanced IVF techniques.

Together, Natalie and Dr Dorofeyeva unpack one of the most talked-about innovations in reproductive medicine — mitochondrial replacement therapy, sometimes misleadingly referred to in the media as “three-parent IVF”.

They explore how MRT works, why it was originally developed to prevent mitochondrial disease, and how it is now being used internationally to help women of advanced maternal age and those who have experienced repeated IVF failure. The conversation also dives into regulation, ethics, access, and why patients are increasingly travelling abroad to access cutting-edge fertility care. This episode is essential listening for anyone navigating infertility, working in fertility care, or interested in how science, law, ethics and society intersect in modern family building.

Key Topics Covered

What mitochondrial replacement therapy (MRT) actually is — in simple terms
Why MRT is not “three-parent IVF”
The science behind mitochondria and egg quality
MRT for mitochondrial disease vs age-related infertility
IVF success rates for women aged 39–52
Why egg quality declines faster than overall health
MRT vs egg donation: key differences
Who is (and isn’t) a good candidate for MRT
Why MRT is legal but tightly restricted in the UK
Fertility tourism and why patients travel abroad for treatment
Ethical questions around age limits and access to fertility care
The future of IVF, innovation, and reproductive medicine

About the Guest

Dr Uliana Dorofeyeva is an obstetrician, gynaecologist, and reproductive endocrinologist with over 18 years of experience in assisted reproductive technology. She is internationally recognised for her work in complex infertility and is a pioneer of mitochondrial replacement programs, helping patients who have exhausted conventional IVF options.

-- About King’s Fertility (Sponsor):

One of London’s most respected IVF clinics, working with King’s College Hospital and King’s College London. King’s Fertility offers NHS and private patients world-leading research, advanced treatment, and compassionate care. Learn more at kingsfertility.co.uk

Connect With Us

Email: info@infertilityinthecity.com
Instagram / LinkedIn / X: @infertilityinthecity
TikTok: @infertility.in.the.city
YouTube: @InFertilityintheCity
Website: www.infertilityinthecity.com

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