This episode provides a comprehensive look at Google DeepMind’s AlphaFold, an artificial intelligence system heralded for solving the 50-year-old protein folding challenge by rapidly and accurately predicting the three-dimensional structures of these crucial biological molecules. This breakthrough, which earned its creators the 2024 Nobel Prize in Chemistry, led to the creation of the AlphaFold Protein Structure Database, which provides open access to over 200 million protein structure predictions for scientists worldwide.