Probiotic Protocols to Heal IBS and SIBO Naturally Introduction As many of my readers know, I have stayed drug free and surgery free from widespread Crohn’s disease for over 25 years. In this series, I interview my long‑time colleague, Natasha Trenev. She is the founder and owner of Natren Probiotics. Many people call her the mother of probiotics. She had probiotic standards read into the U.S. Congressional Record. If our industry followed those standards, probiotic supplements would be far better today. I asked Natasha to join me for a series of deep‑dive calls. I want to bring her knowledge into the mainstream. She has worked in this field for 60 years. She is 77 and still working because she sees so many chronically ill adults and children. We both care deeply. We also use critical thinking. We test ideas. We keep what works. We discard what does not. This blog is based on my in-depth interview with Natasha Trenev, the Mother of Probiotics. You can watch the complete episode in this video: Or you can listen to the podcast: In this post, I share what we discussed about irritable bowel syndrome and small intestinal bacterial overgrowth. I also share the exact protocol I use, with probiotic species and herbal antimicrobials. IBS and SIBO: What They Are and Why They Matter What is Irritable Bowel Syndrome Irritable bowel syndrome is a functional gastrointestinal disorder. Doctors use this term when the digestive tract looks normal on tests. Yet symptoms persist. IBS symptoms include abdominal pain, bloating, gas, diarrhea, constipation, or a mix. These symptoms affect quality of life. Work, school, travel, and relationships suffer. IBS does not always get labeled as inflammatory. But inflammation often plays a role. The gut microbiota becomes imbalanced. Gut motility slows or speeds up. The immune system overreacts or underreacts. Food breaks down into particle sizes that feed bad bacteria. The result is discomfort and distress. What is Small Intestinal Bacterial Overgrowth Small intestinal bacterial overgrowth means too many bacteria live in the small intestine. Bacteria should be dense in the large intestine. The small intestine should hold fewer microbes. In SIBO, fermentation happens too early. This triggers gas, distention, abdominal pain, diarrhea, or constipation. Nutrient absorption suffers. Fatty acids may not get absorbed well. Fat‑soluble vitamins can drop. Many people labeled with IBS also have SIBO. Breath tests try to detect it. These tests can help. They can also miss cases. Clinical trials use them with a placebo group to measure change, but real life is messier. Root causes and risk factors Root causes differ by person. Common risk factors include low stomach acid, chronic stress, past antibiotic therapy, use of proton pump inhibitors, slowed gut motility, food poisoning, and abdominal surgery. Leaky gut, also called increased intestinal permeability, can add to the load. The gut microbiome shifts. The immune response becomes confused. I aim my protocol at these causes. Why I Trust Natasha Trenev’s Perspective Natasha’s standards focus on strain specificity, potency through expiry, and proper delivery. She warns against vague labels like “probiotic blend.” She rejects soil‑based probiotics for most people with IBS or SIBO. She focuses on traditional probiotics with documented safety and clear strain IDs. She has watched the industry change. She has also seen misinformation explode. She and I agree. A colon cleanse is not what most IBS patients need. A careful, staged plan is needed instead. Natasha also reminds us that the intestinal lining is only one cell thick. Those cells turn over every three to five days. Attached bacteria shed with those cells. So regular intake of live microorganisms is needed. This is why daily probiotic supplementation matters. How IBS Feels Day to Day IBS with diarrhea can rule a person’s life. Natasha shared how many people plan routes by bathrooms. The urge hits fast. Acciden