#25 Caloric Restriction Deep-Dive & Longevity Secrets of Long-Lived Animals

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Live Longer World

Aastha Jain Simes

45 episodes

1 week ago

Interviewing scientists at the frontiers of longevity & biology. https://livelongerworld.com/

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Interviewing scientists at the frontiers of longevity & biology. https://livelongerworld.com/

Science

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#25 Caloric Restriction Deep-Dive & Longevity Secrets of Long-Lived Animals | Dr. Steven Austad

Live Longer World

1 hour 8 minutes 36 seconds

3 years ago

#25 Caloric Restriction Deep-Dive & Longevity Secrets of Long-Lived Animals | Dr. Steven Austad

All platforms / Episode Transcript: https://livelongerworld.substack.com/p/saustad

Dr. Steven Austad is a professor in the Healthy Aging department at the University of Alabama and also scientific director of the American Federation for Aging research. He has a fascinating entry into the world of aging research - it all began with training lions!

There are many open questions on the caloric restriction research for enhancing longevity and we dive into that. Further, a lot of Dr. Austad’s work focuses on what long-lived animal species can teach us about living longer and healthier lives. His lab works on exotic species, like clams that live more than 500 years, and hydra that don’t age at all, in order to discover aging treatments. He also tries to uncover the mysteries around why men and women respond differently to longevity therapeutics.

Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/

Find me (Aastha) on Twitter: https://twitter.com/aasthajz

DR. STEVEN AUSTAD LINKS:

Website: https://www.stevenaustad.com/

Twitter: https://twitter.com/StevenAustad

Faculty page: https://www.uab.edu/cas/biology/people/faculty/steven-n-austad

CONNECT WITH AASTHA, LIVE LONGER WORLD:

Website: https://www.livelongerworld.com/

Twitter: https://twitter.com/aasthajz

Newsletter: https://livelongerworld.substack.com/

Instagram: https://www.instagram.com/aasthajz/

TIMESTAMPS:

0:00 Training lions

7:15 Learning from Long-lived species

9:55 Bowhead whales live 200 years

12:55 House sparrows & longevity

14:40 Study "successful" animals

18:10 Naked Mole Rats

20:45 What do bowhead whales die from?

26:05 Why do ocean animals live longest?

31:05 Beyond Caloric Restriction

36:00 Intermittent Fasting & Circadian Rhythm

42:40 Caloric Restriction for Healthy people?

46:24 Will coffee shorten your life?

49:43 The Blue Zone Myth

55:50 Young Blood, I can't get you of out my Mind

1:00:26 Hormones & Health (Growth Hormones for longevity?)

1:05:18 Sex differences in longevity

Episode Show Notes: https://livelongerworld.substack.com/p/saustad

POPULAR EPSIODES:

- Richard Miller on Longevity Supplements: https://youtu.be/42PzfNs9egA

- Matt Kaeberlein on Rapamycin: https://youtu.be/BL67DhNepfg

- Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8

- Nir Barzilai on Metformin & Centenarians: https://youtu.be/YlkBE8N7sl8

- Morgan Levine on Epigenetic Clocks: https://youtu.be/am3YKiTpCHo

Thanks for watching & if you enjoy the episode, let's spread the message on longevity.

You can support my work by sharing, subscribing, leaving a review on Apple podcasts, donating on Patreon, or signing up as a premium member. Aging is universal. Let's unite in this fight. Stay in good health - Aastha.