Dr. Darsh Shah and Dr. Altamash Raja continue their conversation with Dr. Shawn Arent on hormone physiology and performance. They dive into female physiology and menstrual cycle myths, the overlooked role of thyroid and reverse T3, catecholamines and autonomic balance, and the future of performance enhancement with GLP-1s and muscle-preserving drugs. A practical, evidence-based look at optimizing health and performance!
TIMESTAMPS
00:00 Introduction to Medicine Redefined
00:37 Deep Dive into Hormone Physiology
00:54 Female Physiology and Menstrual Cycle
01:03 Thyroid Hormone Optimization
01:12 Catecholamines and Autonomic Balance
01:23 GLP-1 Agonists and Muscle Preservation
01:58 Guest Introduction: Dr. Shawn Arent
02:21 Discussion on Female Physiology
02:29 Menstrual Cycle and Training
07:28 Hormonal Influence on Injury
07:50 Autoregulation in Training
19:03 Thyroid Hormone and Metabolism
33:55 Catecholamines and Training Response
40:55 Sympathetic vs. Parasympathetic Dominance
45:30 Tracking Trends for Better Interventions
45:53 Wearables and Recovery in Rugby
46:55 Debunking Post-Workout Downregulation
50:52 Contextualizing Fitness Advice
57:06 Balancing Training Methods
01:04:30 The Role of IGF-1 in Recovery
01:07:02 GLP-1 Agonists and Muscle Preservation
01:15:22 Myostatin Inhibitors: The Future of Muscle Growth?
01:21:25 Final Thoughts on Health and Performance
The Impact of Menstrual Cycle Phase on Athletes’ Performance: A Narrative Review MDPI
Current evidence shows no influence of women’s menstrual cycle phase on acute strength performance or adaptations to resistance exercise training Frontiers
The Effects of Menstrual Cycle Phase on Exercise Performance in Eumenorrheic Women: A Systematic Review and Meta-Analysis Springer
Influence of Menstrual Cycle Phases on Maximal Strength, Power and High-Intensity Interval Performance – A Systematic Review with Meta-Analysis MDPI
Evidence-Based Training Guidelines for Elite Women Football and Team Sports Human Kinetics
Hormones, Hypertrophy, and Hype: An Evidence-Guided Primer on Endogenous Endocrine Influences on Exercise-Induced Muscle Hypertrophy ESSR
Menstrual Cycle Effects on Sports Performance and Adaptations to Training: A Historical Perspective PubMed
Effect of Estrogen on Musculoskeletal Performance and Injury Risk Frontiers
Anterior Cruciate Ligament Injuries in Female Athletes: A Narrative Review of Prevention, Risk Factors, and Management Bone Jt Open
The Influence of Age on the Effectiveness of Neuromuscular Training to Reduce ACL Injury in Female Athletes: A Meta-Analysis PMC
Catecholamine and Cardiovascular Responses to Exercise: An Update Springer
Effects of Different Training Interventions on Heart Rate Variability in People with Overweight and Obesity: A Systematic Review Frontiers
Blood-Based Biomarkers for Monitoring Workload and Recovery in Athletes Sports Med Open
Changes in Lean Body Mass with the Use of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss and Strategies to Mitigate LBM Loss Wiley
ADA Newsroom: GLP-1 Agonists and Lean Body Mass ADA News
Effects of Subjective and Objective Autoregulation Methods in Resistance Training: A Systematic Review PeerJ
Biomarkers in Sports and Exercise: Tracking Health, Performance, and Recovery in Athletes Springer
Exercise, Training, and the HPT/HPA/HPG Axes in Athletes CSMR
Circulating Testosterone as the Hormonal Basis of Sex Differences in Athletic Performance PMC
Optimizing Health and Athletic Performance for Women Springer
Thank you for listening!