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Mind & Matter
Nick Jikomes
275 episodes
4 days ago
Send us a text Cellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's. TOPICS DISCUSSED: Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR...
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Send us a text Cellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's. TOPICS DISCUSSED: Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR...
Show more...
Science
Education,
Society & Culture
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How & Why Mitochondria Make Their Own Fat | Sara Nowinski | 263
Mind & Matter
57 minutes
1 month ago
How & Why Mitochondria Make Their Own Fat | Sara Nowinski | 263
Send us a text Mitochondrial fatty acid synthesis is a little-known but essential pathway that supports energy production and metabolic health. Summary: Dr. Sara Nowinski explains how mitochondria not only burn fuels to make ATP but also synthesize their own fatty acids inside the matrix; this conserved pathway produces lipoic acid (an essential enzyme cofactor) and longer-chain fats required for proper assembly of the electron transport chain, and disrupting it impairs respiration, glucose h...
Mind & Matter
Send us a text Cellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's. TOPICS DISCUSSED: Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR...