Main Topic: Dr. Marshall confronts the chaos unfolding in Washington DC, where sweeping federal cuts are threatening the very foundations of cancer research and care. Taking us on a journey through some of the life-saving and groundbreaking innovations that all began with federally funded science along with the recent progress in one of the historically toughest cancers—pancreatic cancer. Dr. Marshall asks: How do we fight the dismantling of this important system and protect progress? Interview: In this Candid Conversations episode, Dr. Marshall revisits his conversation with Julie Fleshman, President and CEO of the Pancreatic Cancer Action Network. Julie shares the personal story that sparked her advocacy, the evolution of PanCan, the organization’s pivotal role in driving pancreatic cancer research, patient support, and clinical innovation, reflecting on the progress made for one of the most difficult-to-treat cancers. MedBuzz: Dr. Marshall’s call to action regarding the sweeping federal cuts to key health and research institutions, including the NCI, NIH, and FDA. With sudden firings, hiring freezes, and growing instability in the cancer research ecosystem, he issues a passionate call to the oncology community: speak up, stand together, and push back before decades of progress are undone.