Main Topic: With the continued improvement in neoadjuvant therapies, is surgery becoming less relevant for some patients? In this episode, Dr. John Marshall explores the evolving conversation around quality of life and whether some patients with GI cancers could be spared complex surgeries when there's no evidence of disease. Is the scalpel still best when the tumor appears to be gone? Candid Conversations: From government to academia to industry, Dr Mace Rothenberg’s career has taken a unique path. Now in his third act, he's launching a groundbreaking Museum of Medicine and Biomedical Discovery to restore public trust in science—one immersive, story-driven exhibit at a time. Join Dr John Marshall as he talks with his Obi-Wan Kenobi about career evolution, the power of truth, and why understanding what we don’t know may be just as important as what we do. MedBuzz: A letter from the federal government to Harvard isn’t just bureaucratic noise—it’s a challenge to the core of academic freedom. Dr Marshall unpacks what’s in the letter, why Harvard is pushing back, and what’s at stake for science, healthcare, and the future of free thought in the United States. If academic independence falls, what follows?