In the latest episode of Parallax, Dr Ankur Kalra welcomes Dr Martha Gulati and Dr Anu Lala for a groundbreaking conversation about reimagining heart failure prevention across the entire disease spectrum. Their discussion centres on an innovative scientific statement developed collaboratively between the American Society of Preventive Cardiology and the Heart Failure Society of America - a document that challenges conventional approaches to cardiovascular disease prevention.
Dr Gulati and Dr Lala make a compelling case for expanding prevention beyond atherosclerotic cardiovascular disease (ASCVD) to encompass heart failure, a condition affecting one in four individuals over their lifetime. They introduce the American Heart Association's Cardio Kidney Metabolic (CKM) health framework as a superior model for identifying at-risk patients, explaining how this approach shifts focus from disease management to health optimization. The conversation explores practical implementation strategies, including the new PREVENT risk score, which integrates critical heart failure risk factors like obesity and chronic kidney disease that traditional assessment tools overlook.
Questions and comments can be sent to "podcast@radcliffe-group.com" and may be answered by Ankur in the next episode.
Host: @AnkurKalraMD and produced by: @RadcliffeCardio
Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.
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In the latest episode of Parallax, Dr Ankur Kalra welcomes Dr Martha Gulati and Dr Anu Lala for a groundbreaking conversation about reimagining heart failure prevention across the entire disease spectrum. Their discussion centres on an innovative scientific statement developed collaboratively between the American Society of Preventive Cardiology and the Heart Failure Society of America - a document that challenges conventional approaches to cardiovascular disease prevention.
Dr Gulati and Dr Lala make a compelling case for expanding prevention beyond atherosclerotic cardiovascular disease (ASCVD) to encompass heart failure, a condition affecting one in four individuals over their lifetime. They introduce the American Heart Association's Cardio Kidney Metabolic (CKM) health framework as a superior model for identifying at-risk patients, explaining how this approach shifts focus from disease management to health optimization. The conversation explores practical implementation strategies, including the new PREVENT risk score, which integrates critical heart failure risk factors like obesity and chronic kidney disease that traditional assessment tools overlook.
Questions and comments can be sent to "podcast@radcliffe-group.com" and may be answered by Ankur in the next episode.
Host: @AnkurKalraMD and produced by: @RadcliffeCardio
Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.
EP 131: Beyond Weight Loss: GLP-1s as Cardioprotective Game-Changers in 2025
Parallax by Ankur Kalra
40 minutes 45 seconds
7 months ago
EP 131: Beyond Weight Loss: GLP-1s as Cardioprotective Game-Changers in 2025
In this episode of Parallax, host Dr Ankur Kalra sits down with Dr Ambarish Pandey to explore the transformative role of GLP-1 receptor agonists in cardiovascular medicine. Beyond their well-known effects on weight management, Dr Pandey reveals how these "blockbuster drugs" are fundamentally reshaping cardiovascular disease prevention and treatment, with compelling evidence from the landmark SELECT trial.
The discussion navigates through real-world clinical scenarios where GLP-1s deliver significant cardiovascular benefits, from post-acute coronary events to established atherosclerotic disease. Dr Pandey provides nuanced, evidence-based recommendations for GLP-1 therapy across various heart failure phenotypes, while addressing common comorbidities like atrial fibrillation and obstructive sleep apnea.
Recognizing practical challenges, the conversation offers actionable strategies for medication initiation, dose optimization, and navigating insurance hurdles. The episode concludes with an exciting look toward emerging frontiers, including GLP-1 benefits in chronic kidney disease and innovative metabolic accelerators that could complement existing therapies.
For clinicians seeking to optimize cardio-metabolic care in 2025, this discussion provides essential insights into both current best practices and promising therapeutic horizons.
Disclosures: Dr Ambarish Pandey is a consultant for Novo Nordisk, Eli Lilly, Roche, and Rivus Pharma.
Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode. Host: @AnkurKalraMD and produced by: @RadcliffeCARDIO
Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts: https://www.radcliffecardiology.com/news/parallax-podcast-ankur-kalra-recognised-among-top-medical-podcasts?language_content_entity=en
Parallax by Ankur Kalra
In the latest episode of Parallax, Dr Ankur Kalra welcomes Dr Martha Gulati and Dr Anu Lala for a groundbreaking conversation about reimagining heart failure prevention across the entire disease spectrum. Their discussion centres on an innovative scientific statement developed collaboratively between the American Society of Preventive Cardiology and the Heart Failure Society of America - a document that challenges conventional approaches to cardiovascular disease prevention.
Dr Gulati and Dr Lala make a compelling case for expanding prevention beyond atherosclerotic cardiovascular disease (ASCVD) to encompass heart failure, a condition affecting one in four individuals over their lifetime. They introduce the American Heart Association's Cardio Kidney Metabolic (CKM) health framework as a superior model for identifying at-risk patients, explaining how this approach shifts focus from disease management to health optimization. The conversation explores practical implementation strategies, including the new PREVENT risk score, which integrates critical heart failure risk factors like obesity and chronic kidney disease that traditional assessment tools overlook.
Questions and comments can be sent to "podcast@radcliffe-group.com" and may be answered by Ankur in the next episode.
Host: @AnkurKalraMD and produced by: @RadcliffeCardio
Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.
