Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves.
Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves.
100 episodes
2 months ago
Researchers from across the scientific disciplines share the unpublished stories behind their recently published research, along with the background of their scientific discoveries.
All content for Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves. is the property of Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves. and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Researchers from across the scientific disciplines share the unpublished stories behind their recently published research, along with the background of their scientific discoveries.
Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves.
24 minutes
5 years ago
Silencing an ALS Gene – Tim Miller
How could a gene that causes one type of ALS be switched off? In episode 87, Tim Miller from the Washington University in St. Louis discusses his research into therapies that target the single strands of DNA or RNA which cause many cases of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease. His article “Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS” was published with multiple co-authors on July 9th 2020 in the New England Journal of Medicine.
Silencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim Miller Silencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim MillerSilencing an ALS Gene - Tim Miller {{svg_share_icon}}Click bottom of waveform to add your commentsSubscribe: iTunes | Google Podcasts | Google Play | Spotify | RSS jQuery(document).ready(function ($){var settings_ap7669 = { design_skin: "skin-wave" ,autoplay: "off",disable_volume:"default" ,loop:"off" ,cue: "on" ,embedded: "off" ,preload_method:"metadata" ,design_animateplaypause:"default" ,skinwave_dynamicwaves:"off" ,skinwave_enableSpectrum:"off" ,skinwave_enableReflect:"on",playfrom:"off",default_volume:"default",disable_scrub:"off",soundcloud_apikey:"" ,skinwave_comments_enable:"on",settings_php_handler:window.ajaxurl,skinwave_mode:"alternate",skinwave_wave_mode:"canvas",pcm_data_try_to_generate: "on","pcm_notice": "off","notice_no_media": "on",design_color_bg: "111111",design_color_highlight: "FF4C65",skinwave_wave_mode_canvas_waves_number: "3",skinwave_wave_mode_canvas_waves_padding: "1",skinwave_wave_mode_canvas_reflection_size: "0.25",skinwave_wave_mode_canvas_mode:"normal",preview_on_hover:"off",skinwave_comments_playerid:"7669",embed_code:""
,enable_embed_button:"on",php_retriever:"https://www.parsingscience.org/wp-content/plugins/dzs-zoomsounds/soundcloudretriever.php" }; try{ dzsap_init(".ap_idx_7669_126",settings_ap7669); }catch(err){ console.warn("cannot init player", err); } });
Websites and other resources
NEJM editorial on Tim's study
Tim's lab website
Video of Tim discussing new therapies for ALS:
Clips available include ...
Full episode with available download
More coming soon
🔊 Access bonus content here.
Support us for as little as $1 per month at Patreon. Cancel anytime.
We’re not a registered tax-exempt organization, so unfortunately gifts aren't tax deductible.
Hosts / Producers
Ryan Watkins & Doug Leigh
How to Cite
Watkins, R., Leigh, D., & Miller, T.. (2020). Parsing Science - Silencing an ALS Gene. doi: 10.6084/m9.figshare.13232651
Music
What’s The Angle? by Shane Ivers
Transcript
Parsing Science: The unpublished stories behind the world’s most compelling science, as told by the researchers themselves.
Researchers from across the scientific disciplines share the unpublished stories behind their recently published research, along with the background of their scientific discoveries.
