In this episode, Dr. Derek Paul, physician-turned-founder and CEO of Glass Health, joins Elsa to discuss the mindset shift from medicine to entrepreneurship—and how clinical reasoning can shape the way we build AI. Backed by Y Combinator and Breyer Capital, Glass Health began as a digital notebook for doctors and evolved into a leading platform for AI-powered clinical decision support.

Derek explains how physicians’ structured approach to diagnosis—testing hypotheses, managing uncertainty, and learning from feedback—translates directly into effective product design and company building. He shares how Glass ensures medical accuracy and safety, what it means to train AI models with physician expertise, and how startups can navigate FDA frameworks, EHR integrations, and data compliance while maintaining speed and innovation.

From leaving the clinic to leading an AI company, Derek reflects on the cognitive frameworks that drive both good medicine and good startups—and why mastering uncertainty is the core skill behind both.