Advanced Micro Devices ($AMD) has evolved from Intel’s scrappy underdog into a bona fide chip powerhouse. In this episode, we trace the turnaround under CEO Lisa Su—the shift to high-performance computing with Zen/Ryzen and EPYC, a fabless model that leverages TSMC, and a diversified footprint across data centers, PCs, gaming (including console semi-custom chips), and embedded markets. We unpack AMD’s bold push into AI with its Instinct accelerators and cloud partnerships, set against fierce rivals like Intel and the dominant Nvidia (and the CUDA ecosystem lock-in), plus execution, supply-chain and geopolitical risks. Is AMD the resilient challenger primed to keep disrupting incumbents, or a high-stakes contender in an unforgiving, execution-driven race?

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