Natural killer cells are gaining serious momentum as a promising form of cell therapy in the fight against cancer. This week, we dive deep into the fascinating world of natural killer (NK) cells, our immune system’s fast acting first responders, and how they are being reengineered to take on some of the toughest cancers. 

We explore how NK cells work, why cancer manages to evade them, and what researchers are doing to overcome these hurdles, from memory like NK cells to powerful CAR engineered therapies and next generation strategies like bispecific engagers and extracellular vesicles. Tune in to learn how these cellular assassins are being transformed into a new wave of cancer fighting tools.

Featured Articles: Natural Killer Cell-Based Cancer Immunotherapy: From Basics to Clinical Trials (https://doi.org/10.1186/s40164-024-00561-z)

Building a Better Defense: Expanding and Improving Natural Killer Cells for Adoptive Cell Therapy (https://doi.org/10.3390/cells13050451)