In this episode, we explore the role of goal-setting and purposeful behaviour in Buddhist contemplative practice. While many traditions emphasize letting go, Buddhist training is also deeply structured by intentionality, effort, and purposeful cultivation. Nadav Amir brings a computational neuroscience perspective to these questions, examining how minds generate goals, how agency emerges, and how these processes relate to frameworks from early Buddhist epistemology and ethics. Together, we discuss paradoxes of striving, the tension between effort and non-attachment, and what modern neuroscience can tell us about intention on the contemplative path.