The YouTube video "Choose Wisely! 6 Very Profitable Businesses to Start" by James Sinclair provides a business-oriented perspective on profitable business models. The video creator, who has over 20 years of experience in business, outlines six specific types of businesses that he believes are likely to be profitable. These include day nurseries, food service businesses, contract catering, commercial property rentals, niche wholesale businesses, and commercial hygiene and waste services. The video highlights factors that contribute to the profitability of these models, such as predictable cash flow, repeat customers, high barriers to entry, and opportunities for roll-up acquisitions by larger companies. Sinclair emphasizes that these businesses have a strong likelihood of success due to their inherent characteristics and potential for growth.