In this episode of the Longevity Game Podcast, Michael Ward discusses the complexities and misconceptions surrounding hormone replacement therapy, particularly focusing on estradiol in both women and men. He critiques the Women's Health Initiative study and its flawed conclusions, emphasizing the benefits of bioidentical hormones and the risks associated with improper hormone management. The conversation highlights the importance of individualized treatment and the need for updated information in medical practice.Takeaways-Hormone replacement therapy is often misunderstood and misrepresented.-The Women's Health Initiative study led to unnecessary fear around hormone therapy.-Bioidentical hormones can significantly improve quality of life for women.-Estradiol therapy has been shown to reduce risks of Alzheimer's and heart disease.-Men also need to be cautious about estrogen levels when on testosterone therapy.-Aromatase inhibitors can have negative effects on men's health if used improperly.-Not all hormone therapies are created equal; classification errors can lead to poor outcomes.-Individualized treatment is crucial for effective hormone management.-Education and updated research are essential for healthcare providers.-Books like 'Hormone Havoc' can provide valuable insights into hormone therapy.Sound bites"91,000 women died needlessly as a result.""Estradiol therapy decreases risk of Alzheimer's.""Check out Hormone Havoc by Dr. Terry."Chapters00:00 Introduction to Hormone Replacement Therapy06:22 Understanding Estradiol in Women13:00 Conclusion and RecommendationsFor Contact, Sponsorship, Press, Support:*Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com*Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com*Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com