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The Observable Unknown
Dr. Juan Carlos Rey
54 episodes
1 day ago
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Science
Religion & Spirituality,
Society & Culture
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Science
Religion & Spirituality,
Society & Culture
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Interlude XX – The Whispering Cells: Astrocytes and the Secret Mind
The Observable Unknown
4 minutes
1 month ago
Interlude XX – The Whispering Cells: Astrocytes and the Secret Mind
In this quietly radical interlude, Dr. Juan Carlos Rey of crowscupboard.com invites you into the hidden orchestra of the brain - the immense realm of glial cells: astrocytes, oligodendrocytes, and microglia. We have long worshipped the bright-firing neurons, but these non-neuronal cells may in fact hold the deeper language of consciousness.Pioneering work by Dr. R. Douglas Fields at the National Institutes of Health revealed that experience-driven myelination - the wrapping and reshaping of axons by oligodendrocytes - is guided by neural activity rather than passive development.Meanwhile, Dr. Maiken Nedergaard at the University of Rochester and the University of Copenhagen uncovered the glymphatic system - a glia-driven clearing network that operates primarily during sleep, suggesting that astrocytes oversee brain detoxification and restoration.This episode explores how these whispering cells sculpt learning, mood, intuition, and memory via calcium-wave signalling rather than rapid electrical spikes. We traverse from deep sleep to white matter, from silent structural rearrangement to the possible biological roots of insight.The observable unknown here is profound: perhaps the true architecture of mind is not in the fire of neurons, but in the hush of glia - the vast cellular grid that conducts all thought, emotion, and awareness without a single visible spark.Join Dr. Rey and discover what your brain keeps whispering beneath your everyday consciousness.
The Observable Unknown