Check your testosterone levels: https://www.manual.co/smith I help small businesses make money online: https://www.jamessmith.business Try Neutonic: https://www.neutonic.com/jamessmith Free trial: Online coaching app: https://www.affordableonlinecoaching.com Scientist and author Dr. Andrew Steele joins James Smith to tackle the problem with aging and why dying of “old age” might one day be seen as a preventable condition. Andrew breaks down the science of longevity, the myths around “anti-aging,” and the difference between fundamental research and influencer nonsense. He explains how new medical breakthroughs could help humans live healthier for far longer, but also why the hype around biohacking and “forever pills” is getting dangerously ahead of the science. They explore the ethical, political, and even economic implications of extending human life, from billionaire-funded immortality labs to the fear that longevity could deepen inequality. Andrew reveals what the real science shows about genes, lifestyle, and luck; why exercise is still the best anti-aging treatment we have; and how new drugs like GLP-1 agonists could transform global health and longevity. He explains: ◼️ Why 90% of deaths in rich countries are caused by aging ◼️ The truth about genetic luck vs lifestyle choices ◼️ How longevity drugs could revolutionise healthcare ◼️ Why “anti-ageing” influencers are misleading the public ◼️ The shocking economics of living to 100… or beyond Chapters 00:00 Why Men Die Earlier Than Women 01:31 The Real Problem With Aging 02:36 Separating Longevity Fact From Fiction 05:23 What Your Face Reveals About Health 08:50 How Much Do Genetics Actually Matter? 12:32 Do Weight Loss Drugs Slow Aging? 16:48 The Stigma Of Weight Loss Drugs 19:01 James’ Experience Taking Weight Loss Drugs 22:37 Is Taking Ozempic "Cheating"? 27:02 The Reality Of Maintaining Weight Loss 31:26 Why Modern Diets Are Failing 35:26 The Future Of Longevity Medicine 39:36 Will Longevity Increase Retirement Age? 43:01 The Problem With Bryan Johnson’s Protocol 46:44 Is Biohacking Just An Eating Disorder? 52:01 The Dangers Of Over-Optimizing Health 56:36 Does Health Anxiety Shorten Lifespan? 01:01:46 The Truth About HRT For Women 01:06:51 Does Testosterone Shorten Men’s Lives? 01:12:50 Why Eunuchs Live Longer Than Men 01:17:56 The Philosophy Of Living Forever 01:27:11 The Most Effective Longevity Habits 01:29:56 Does Intermittent Fasting Increase Longevity? 01:38:36 The Most Promising Anti-Aging Drug 01:45:36 The Economic Case For Curing Aging Welcome to "The Problem With" where each week we look into a problem to get a better understanding of it. This podcast has no sponsors, only my businesses and investments. Please check out the links below. I'm on a mission to help men check their levels of Testosterone, more info here: https://www.manual.co/smith I help small businesses make money online: https://www.jamessmith.business Please check out and try Neutonic here: https://www.neutonic.com/jamessmith For a free trial of my online personal training app go here: https://www.affordableonlinecoaching.com Learn more about your ad choices. Visit podcastchoices.com/adchoices