The Proof Podcast is a space for science-based conversation. Together with his guests, Simon Hill, a qualified physiotherapist and nutritionist, explores the health and longevity benefits that come with mastering physical exercise, nutrition, mindfulness, recovery, sleep, and alignment. Facts, nuance and trustworthy recommendations minus the hyperbole. All the proof you need to live better for longer.
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The Proof Podcast is a space for science-based conversation. Together with his guests, Simon Hill, a qualified physiotherapist and nutritionist, explores the health and longevity benefits that come with mastering physical exercise, nutrition, mindfulness, recovery, sleep, and alignment. Facts, nuance and trustworthy recommendations minus the hyperbole. All the proof you need to live better for longer.
Does Keto Accelerate Heart Disease? What the New Study Didn’t Tell You | Simon Hill, Msc, Bsc
The Proof with Simon Hill
50 minutes
2 months ago
Does Keto Accelerate Heart Disease? What the New Study Didn’t Tell You | Simon Hill, Msc, Bsc
In this solo episode, I unpack the controversial new KETO-CTA study and why its conclusions about cholesterol, ApoB, and ketogenic diets aren’t as clear as they seem.
We break down what the study really found, how it was communicated, and what it means if you (or someone you care about) is following a high-fat, low-carb diet with elevated LDL-C.
With expert commentary from Dr. Alan Flanagan, we explore:
Who Lean Mass Hyper-Responders (LMHRs) are
Why the study isn’t actually a “trial”
The missing data on plaque progression and what was left out
What non-calcified plaque volume (NCPV) tells us
Whether this study really challenges ApoB’s role in heart disease
Why communication matters and how headlines can mislead
What this means for keto diets, cardiovascular risk, and informed decisions
If you found this valuable, please share it or leave a review. Every share helps the truth cut through the noise.
Intro: Can You Be “Healthy” with Sky-High LDL on Keto? (00:00)
What the Keto CTA Study Was Trying to Prove (01:36)
The Problem: This Wasn’t Actually a Clinical Trial (03:57)
APOB Focused, But Not Pre-Registered: Red Flag #1 (07:58)
Real Plaque Progression Numbers: 4x Faster Than Healthy Controls (09:16)
So… Does ApoB Matter or Not? (17:50)
How the Study Was Communicated to the Public (26:03)
What the Headlines Should Actually Say (37:05)
Final Thoughts from Dr. Carvallo and Dr. Flanagan (38:06)
Key Takeaways (40:37)
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Simon Hill, MSc, BSc (Hons)
Creator of theproof.com
Host of The Proof with Simon Hill
Author of The Proof is in the Plants
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The Proof with Simon Hill
The Proof Podcast is a space for science-based conversation. Together with his guests, Simon Hill, a qualified physiotherapist and nutritionist, explores the health and longevity benefits that come with mastering physical exercise, nutrition, mindfulness, recovery, sleep, and alignment. Facts, nuance and trustworthy recommendations minus the hyperbole. All the proof you need to live better for longer.
