Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
CME Available: Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Nursing CE Contact Hours Available: Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance. Other healthcare professionals will receive a certificate of attendance.
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Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
CME Available: Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Nursing CE Contact Hours Available: Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance. Other healthcare professionals will receive a certificate of attendance.
When sepsis strikes, the damage doesn’t always end with the infection. Nicole Kupchik is joined by Dr. Mitchell Elkind from the American Heart Association to explore how inflammation during sepsis can overwhelm the cardiovascular system, causing arrhythmias, heart failure, and even stroke. From acute AFib to long-term heart damage and the hidden role of cytokines, we dig into the silent injuries that outlast recovery. Plus, we hear a powerful firsthand story from sepsis survivor Mary Millard, whose cardiac journey illustrates the complex chain reaction that infection can trigger.
Featured Guests:
Mitchell Elkind, MD, MS, FAHA (X: AHAScience), is the American Heart Association’s Chief Clinical Science Officer and serves as the senior staff science leader for all Association initiatives related to stroke, brain health, and new integrated efforts including cardio-renal-metabolic health.
Key Takeaways:
A startling percentage of sepsis patients experience heart complications, including those with no cardiac history
Sepsis survivors may carry hidden cardiovascular risks for months, or even years, after discharge.
Inflammation and clotting are deeply intertwined, and both can leave permanent marks on the heart and brain.
Sepsis may someday be recognized as a formal cardiovascular risk factor, just like diabetes or hypertension.
Research into statins, GLP-1s, and anti-inflammatory treatments is opening new doors for post-sepsis care.
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Get in Touch: info@sepsis.org
Or Visit Us At: SepsisPodcast.org
Connect with Nicole on Socials: @nicolekupchik
Connect with Sepsis Alliance on Socials: @sepsisalliance
To Learn More About Sepsis, Visit Sepsis.org
Produced by: Human Content and Sepsis Alliance
Sepsis is a life-threatening emergency that happens when your body’s response to an infection damages vital organs and, often, causes death. In other words, it’s your body’s overactive and toxic response to an infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment. Sepsis can lead to severe sepsis and septic shock.
Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The Sepsis Spectrum
Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
CME Available: Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Nursing CE Contact Hours Available: Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance. Other healthcare professionals will receive a certificate of attendance.
