“So what is a drug?” asks scholar-essayist Justin Smith-Ruiu in this week’s episode of The World in Time. “It’s a dry good that is transported and then sold in a particular measurable unit, and until you have those units of measurement and standardization for the purposes of commercial exchange, you don’t really have drugs. Of course, you have ayahuasca and fly agaric and whatever else, and you have people, at least going back to the Paleolithic, consuming these. But you don’t have the system of commodities that makes drugs a particularly modern phenomenon. And what happens as they are commodified—which you could also describe in the same way as saying what happens as they are transformed into drugs, as ayahuasca, for example, is transformed into a drug—is that they’re pulled out of the cultural and ritual context in which they had once made sense, and turned into intoxicants, turned into substances, the purpose of which is to remove you from the burdens of your life.” This week on the podcast, Donovan Hohn revisits the topics of Intoxication (Winter 2012) and Disaster (Spring 2016), speaking first with Justin Smith-Ruiu, author of the forthcoming book On Drugs: Psychedelics, Philosophy, and the Nature of Reality, about the history of drugs and the history of California; about trips, long and strange, good and bad; and about Smith-Ruiu’s experiments—in philosophy and literary nonfiction as well as in psychopharmacology. Later in the episode, Hohn speaks with poet Rachel Richardson about California on fire; about the ways technology gives us a distorted, fishbowl view of disasters, natural and otherwise; about the documentary poetics of C.D. Wright; and about the classical Greek poetic form of the cento, two contemporary examples of which Richardson shares from her new collection, Smother.