Ayush Noori, Ashton Trotman-Grant, Michael Chavez, Seth Bannon
24 episodes
9 months ago
Translation is the process of turning basic scientific research into therapies that cure disease, new sources of energy that heal the planet, and other things that move the world forward.
The Translation Podcast takes a deep dive into scientific advancements with a massive potential to improve society. We talk directly with the people advancing the science with their own hands and minds, and focus on how we can translate the science from the bench to the benefit of all.
Initially centered on biology and synthetic biology, we’ll talk with the most promising young scientists in the field. We aim to demystify the science for a general audience and to shine a light on how great science turns into great business. We hope these discussions will inspire scientists, entrepreneurs, and investors to help commercialize breakthrough research.
If you’re an author of an upcoming paper in biology or know of any interesting papers dropping soon and want to hear from the authors, drop us an email at translation@50y.com.
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Translation is the process of turning basic scientific research into therapies that cure disease, new sources of energy that heal the planet, and other things that move the world forward.
The Translation Podcast takes a deep dive into scientific advancements with a massive potential to improve society. We talk directly with the people advancing the science with their own hands and minds, and focus on how we can translate the science from the bench to the benefit of all.
Initially centered on biology and synthetic biology, we’ll talk with the most promising young scientists in the field. We aim to demystify the science for a general audience and to shine a light on how great science turns into great business. We hope these discussions will inspire scientists, entrepreneurs, and investors to help commercialize breakthrough research.
If you’re an author of an upcoming paper in biology or know of any interesting papers dropping soon and want to hear from the authors, drop us an email at translation@50y.com.
Brewing a Life-Saving Drug in Yeast with Prashanth Srinivasan
Translation
53 minutes 26 seconds
4 years ago
Brewing a Life-Saving Drug in Yeast with Prashanth Srinivasan
Small molecules are a pillar of human health, making up a majority of the drugs we have in our healthcare arsenal. Many of these drugs are obtained by utilizing synthetic chemistry to modify the composition of some small molecule found in nature. Derivatives of tropane alkaloids, for example, alleviate neuromuscular disorders and are derived from a chemical found in nightshade plants. However, sourcing these plants have become exceedingly difficult as climate change, the pandemic, and geopolitics ravage the supply chain. Looking to overcome these challenges, Prashanth recapitualed the biochemical pathway that makes these tropane alkaloids in yeast. In the most complex feat of metabolic engineering to date, Prashanth can make these life-saving drugs in a bioreactor, insulated from the issues that make them expensive and in short-supply.
Translation
Translation is the process of turning basic scientific research into therapies that cure disease, new sources of energy that heal the planet, and other things that move the world forward.
The Translation Podcast takes a deep dive into scientific advancements with a massive potential to improve society. We talk directly with the people advancing the science with their own hands and minds, and focus on how we can translate the science from the bench to the benefit of all.
Initially centered on biology and synthetic biology, we’ll talk with the most promising young scientists in the field. We aim to demystify the science for a general audience and to shine a light on how great science turns into great business. We hope these discussions will inspire scientists, entrepreneurs, and investors to help commercialize breakthrough research.
If you’re an author of an upcoming paper in biology or know of any interesting papers dropping soon and want to hear from the authors, drop us an email at translation@50y.com.
