This podcast aims to present you research articles recently published in the field of immunology and tumor immunology in an journal club format.
Disclaimer: the comments provided are strictly personal and do not represent the scientific positions or scientific orientations of the institutions where the authors of this podcast work or have worked in the past.
The audio soundtrack is provide by Magnatunes.com. I used the track "Innocent Murmur" from the album "First album", produced by the progressive jazz band
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This podcast aims to present you research articles recently published in the field of immunology and tumor immunology in an journal club format.
Disclaimer: the comments provided are strictly personal and do not represent the scientific positions or scientific orientations of the institutions where the authors of this podcast work or have worked in the past.
The audio soundtrack is provide by Magnatunes.com. I used the track "Innocent Murmur" from the album "First album", produced by the progressive jazz band
A diversified memory repertoire from a single naive T cell
Tumor Immunology Round Table
19 minutes
17 years ago
A diversified memory repertoire from a single naive T cell
Hello
In this edition of the podcast I will discuss a paper published by
Stemberger and collaborators in the journal Immunity called "A
single naive CD8+ T cells precursor can develop into diverse effector
and memory subset" vol 27, pag 987 of December 2007.
In this very interesting paper the authors redraw the concepts of
memory T cells differentiation from naive T cells, developping a
successfull model of transfer of an single naive T cell precursor. The
paper shows that this single antigen specific naive T cell precursor
can give rise to an diversified memory T cell responses including all
subsets (central memory (CD62L positive, CD127 posit) and effector
memory (CD62L negative, CD127 positive) T cells) upon antigen challenge.
Importantly the kind of memory responses were equivalent in frequency
to the ones generated by the host mice (containing a normal size naive
pool of antigen specific T cells) against an antigenic protein.
See you next time.
PS: The audio has "clicks" artifacts that I don't know the origin. I
apologize for that.
Tumor Immunology Round Table
This podcast aims to present you research articles recently published in the field of immunology and tumor immunology in an journal club format.
Disclaimer: the comments provided are strictly personal and do not represent the scientific positions or scientific orientations of the institutions where the authors of this podcast work or have worked in the past.
The audio soundtrack is provide by Magnatunes.com. I used the track "Innocent Murmur" from the album "First album", produced by the progressive jazz band
