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What The If?
Philip Shane, Matt Stanley, Gabrielle Paniccia
431 episodes
6 days ago
We're taking a break this week while Philip recovers from the 'double-whammy' of flu and COVID boosters. (Science works, but sometimes it makes you nap!) However, we couldn't let January 7th pass unnoticed. On this day in 1610, Galileo first spotted Jupiter's moon, Io. To celebrate, we’ve unlocked the vault for an encore of one of our most popular episodes ever. Strap in for a tour of a lava-covered world with Robin Andrews in... "Walking on IO". ---- DR. ROBIN GEORGE ANDREWS, science writer for The NY Times, National Geographic, Scientific American, and many more, joins us with an IF that'll keep you on your feet: What The IF we could walk on Jupiter's ultra volcanic moon, IO? Would you walk on a hot pizza? If so, you're ready for the trip! The views of Jupiter would be spectacular, but bring your kevlar umbrella because lava's gonna come flyin' out of the sky. One of the most spectacular places in the solar system, Io is also terribly mysterious, bizarre, and confusing to even the greatest scientists of our time. Pack your bags, bring some galoshes, and let's go! --- Robin Andrews is a doctor of experimental volcanology, a full-time freelance science journalist, a part-time photographer, a scientific consultant, an occasional lecturer, public speaker and explain-how-volcanoes-work TV guest, as well as a pending author of a rather curious book. He can tell you exactly how powerful the Death Star is, how cryovolcanoes on alien worlds work, why a supervolcano probably isn’t what you think it is, and why the Moon is shrinking. His work has appeared in THE NEW YORK TIMES, THE ATLANTIC, NATIONAL GEOGRAPHIC, SCIENTIFIC AMERICAN, EARTHER, GIZMODO, FORBES, THE VERGE, ATLAS OBSCURA, DISCOVER MAGAZINE, WIRED and elsewhere. VISIT his website: robingeorgeandrews.com -------- REVIEW the show: itunes.apple.com/podcast/id1250517051?mt=2&ls=1 SUBSCRIBE for free: pod.link/1250517051 EINSTEIN'S WAR by our very own MATT STANLEY is on sale now! The Washington Post says "Stanley is a storyteller par excellence." A starred review recipient from KIRKUS, PUBLISHER'S WEEKLY, and BOOKLIST. www.penguinrandomhouse.com/books/60811…81524745417 Thanks & Keep On IFFin'! -- Philip, Matt & Gaby
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We're taking a break this week while Philip recovers from the 'double-whammy' of flu and COVID boosters. (Science works, but sometimes it makes you nap!) However, we couldn't let January 7th pass unnoticed. On this day in 1610, Galileo first spotted Jupiter's moon, Io. To celebrate, we’ve unlocked the vault for an encore of one of our most popular episodes ever. Strap in for a tour of a lava-covered world with Robin Andrews in... "Walking on IO". ---- DR. ROBIN GEORGE ANDREWS, science writer for The NY Times, National Geographic, Scientific American, and many more, joins us with an IF that'll keep you on your feet: What The IF we could walk on Jupiter's ultra volcanic moon, IO? Would you walk on a hot pizza? If so, you're ready for the trip! The views of Jupiter would be spectacular, but bring your kevlar umbrella because lava's gonna come flyin' out of the sky. One of the most spectacular places in the solar system, Io is also terribly mysterious, bizarre, and confusing to even the greatest scientists of our time. Pack your bags, bring some galoshes, and let's go! --- Robin Andrews is a doctor of experimental volcanology, a full-time freelance science journalist, a part-time photographer, a scientific consultant, an occasional lecturer, public speaker and explain-how-volcanoes-work TV guest, as well as a pending author of a rather curious book. He can tell you exactly how powerful the Death Star is, how cryovolcanoes on alien worlds work, why a supervolcano probably isn’t what you think it is, and why the Moon is shrinking. His work has appeared in THE NEW YORK TIMES, THE ATLANTIC, NATIONAL GEOGRAPHIC, SCIENTIFIC AMERICAN, EARTHER, GIZMODO, FORBES, THE VERGE, ATLAS OBSCURA, DISCOVER MAGAZINE, WIRED and elsewhere. VISIT his website: robingeorgeandrews.com -------- REVIEW the show: itunes.apple.com/podcast/id1250517051?mt=2&ls=1 SUBSCRIBE for free: pod.link/1250517051 EINSTEIN'S WAR by our very own MATT STANLEY is on sale now! The Washington Post says "Stanley is a storyteller par excellence." A starred review recipient from KIRKUS, PUBLISHER'S WEEKLY, and BOOKLIST. www.penguinrandomhouse.com/books/60811…81524745417 Thanks & Keep On IFFin'! -- Philip, Matt & Gaby
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Science
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AI Viruses
What The If?
54 minutes 18 seconds
3 months ago
AI Viruses
Scientists just used artificial intelligence to design the world's first AI-generated viruses capable of hunting down and killing drug-resistant strains of E. coli. These bacteriophages look like tiny alien pineapples with syringes that stab bacterial cells, and they're just the beginning of AI-created life. From Matt's dream of dish-cleaning bacteria that won't eat you (hopefully) to the accidental discovery that trying to make super purple petunias actually created white flowers instead, this episode explores what the if happens when computers start writing genetic code. Discover why we're running out of antibiotics, how a virus with only 11 genes works, and why your future dish soap bottle might say "now with AI inside." Plus, learn about the scientist who tried to engineer the most purple petunias ever and accidentally won a Nobel Prize instead. Based on "World's First AI Designed Viruses: A Step Towards AI Generated Life" by Katie Kavanagh, published in Nature on September 19, 2025. https://www.nature.com/articles/d41586-025-03055-y Matt also mentions a book worth checking out during the episode: "The Genealogy of a Gene: Patents, HIV/AIDS, and Race" by Myles W. Jackson, published by MIT Press. The book explores how intellectual property law has transformed scientific research through the fascinating story of the CCR5 gene, examining everything from Big Pharma to personalized medicine. Learn more at https://mitpress.mit.edu/9780262533782/the-genealogy-of-a-gene/ --- Find out more about Gaby's science fiction short story! Here are the links for the anthology. The physical copy can be ordered here : https://www.neonhemlock.com/books/luminescent-machinations-queer-tales-of-monumental-invention The ebook can be ordered here: https://www.neonhemlock.com/ebooks/luminescent-machinations-queer-tales-of-monumental-invention
What The If?
We're taking a break this week while Philip recovers from the 'double-whammy' of flu and COVID boosters. (Science works, but sometimes it makes you nap!) However, we couldn't let January 7th pass unnoticed. On this day in 1610, Galileo first spotted Jupiter's moon, Io. To celebrate, we’ve unlocked the vault for an encore of one of our most popular episodes ever. Strap in for a tour of a lava-covered world with Robin Andrews in... "Walking on IO". ---- DR. ROBIN GEORGE ANDREWS, science writer for The NY Times, National Geographic, Scientific American, and many more, joins us with an IF that'll keep you on your feet: What The IF we could walk on Jupiter's ultra volcanic moon, IO? Would you walk on a hot pizza? If so, you're ready for the trip! The views of Jupiter would be spectacular, but bring your kevlar umbrella because lava's gonna come flyin' out of the sky. One of the most spectacular places in the solar system, Io is also terribly mysterious, bizarre, and confusing to even the greatest scientists of our time. Pack your bags, bring some galoshes, and let's go! --- Robin Andrews is a doctor of experimental volcanology, a full-time freelance science journalist, a part-time photographer, a scientific consultant, an occasional lecturer, public speaker and explain-how-volcanoes-work TV guest, as well as a pending author of a rather curious book. He can tell you exactly how powerful the Death Star is, how cryovolcanoes on alien worlds work, why a supervolcano probably isn’t what you think it is, and why the Moon is shrinking. His work has appeared in THE NEW YORK TIMES, THE ATLANTIC, NATIONAL GEOGRAPHIC, SCIENTIFIC AMERICAN, EARTHER, GIZMODO, FORBES, THE VERGE, ATLAS OBSCURA, DISCOVER MAGAZINE, WIRED and elsewhere. VISIT his website: robingeorgeandrews.com -------- REVIEW the show: itunes.apple.com/podcast/id1250517051?mt=2&ls=1 SUBSCRIBE for free: pod.link/1250517051 EINSTEIN'S WAR by our very own MATT STANLEY is on sale now! The Washington Post says "Stanley is a storyteller par excellence." A starred review recipient from KIRKUS, PUBLISHER'S WEEKLY, and BOOKLIST. www.penguinrandomhouse.com/books/60811…81524745417 Thanks & Keep On IFFin'! -- Philip, Matt & Gaby